2023

• Spatial and Temporal Protein Modules Signatures Associated with Alzheimer Disease in 3xTg-AD Mice Are Restored by Early Ubiquinol Supplementation. Llanos-González E, Sancho-Bielsa FJ, Frontiñán-Rubio J, Rabanal-Ruíz Y, García-Carpintero S, Chicano E, Úbeda-Banon I, Flores-Cuadrado A, Giménez-Llort L, Alcaín FJ, Peinado JR, Durán-Prado M. Antioxidants (Basel). 2023 Mar 19;12(3):747. doi: 10.3390/antiox12030747.PMID: 36978996 
• NDP52 acts as a redox sensor in PINK1/Parkin-mediated mitophagy. Kataura T, Otten EG, Rabanal-Ruiz Y, Adriaenssens E, Urselli F, Scialo F, Fan L, Smith GR, Dawson WM, Chen X, Yue WW, Bronowska AK, Carroll B, Martens S, Lazarou M, Korolchuk VI. EMBO J. 2023 Mar 1;42(5):e111372. doi: 10.15252/embj.2022111372. Epub 2022 Dec 14.PMID: 36514953 
• Assessment of genotoxicity induced by subchronic exposure to graphene in HaCaT human skin cell line. Frontiñan-Rubio J, García-Carpintero S, González VJ, Vázquez E, Durán-Prado M. Nanotoxicology. 2023 Feb;17(1):42-61. doi: 10.1080/17435390.2023.2183653. Epub 2023 Mar 11.PMID: 36905634
• CoQ₁₀ reduces glioblastoma growth and infiltration through proteome remodeling and inhibition of angiogenesis and inflammation. Frontiñán-Rubio J, Llanos-González E, García-Carpintero S, Peinado JR, Ballesteros-Yáñez I, Rayo MV, de la Fuente J, Pérez-García VM, Perez-Romasanta LA, Malumbres M, Alcaín FJ, Durán-Prado M. Cell Oncol (Dordr). 2023 Feb;46(1):65-77. doi: 10.1007/s13402-022-00734-0. Epub 2022 Nov 2.PMID: 36319818 
• Easy and Versatile Synthesis of Bulk Quantities of Highly Enriched ¹³C-Graphene Materials for Biological and Safety Applications. González V, Frontiñan-Rubio J, Gomez MV, Montini T, Durán-Prado M, Fornasiero P, Prato M, Vázquez E. ACS Nano. 2023 Jan 10;17(1):606-620. doi: 10.1021/acsnano.2c09799. Epub 2022 Dec 20.PMID: 36538410

2022

• Influence of Protein Carbonylation on Human Adipose Tissue Dysfunction in Obesity and Insulin Resistance. Navarro-Ruiz MC, Soler-Vázquez MC, Díaz-Ruiz A, Peinado JR, Nieto Calonge A, Sánchez-Ceinos J, Tercero-Alcázar C, López-Alcalá J, Rangel-Zuñiga OA, Membrives A, López-Miranda J, Malagón MM, Guzmán-Ruiz R. Biomedicines. 2022 Nov 24;10(12):3032. doi: 10.3390/biomedicines10123032.PMID: 36551793 
• APOE in the bullseye of neurodegenerative diseases: impact of the APOE genotype in Alzheimer’s disease pathology and brain diseases. Fernández-Calle R, Konings SC, Frontiñán-Rubio J, García-Revilla J, Camprubí-Ferrer L, Svensson M, Martinson I, Boza-Serrano A, Venero JL, Nielsen HM, Gouras GK, Deierborg T. Mol Neurodegener. 2022 Sep 24;17(1):62. doi: 10.1186/s13024-022-00566-4.PMID: 36153580 
• Genomic targets and selective inhibition of DNA methyltransferase isoforms. Sae-Lee C, Barrow TM, Colicino E, Choi SH, Rabanal-Ruiz Y, Green D, Korolchuk VI, Mathers JC, Byun HM. Clin Epigenetics. 2022 Aug 20;14(1):103. doi: 10.1186/s13148-022-01325-4.PMID: 35987848 
• Subchronic Graphene Exposure Reshapes Skin Cell Metabolism. Frontiñan-Rubio J, Llanos-González E, González VJ, Vázquez E, Durán-Prado M. J Proteome Res. 2022 Jul 1;21(7):1675-1685. doi: 10.1021/acs.jproteome.2c00064. Epub 2022 May 25.PMID: 35611947 
• Sequestration of TDP-43^216-414 Aggregates by Cytoplasmic Expression of the proSAAS Chaperone. Peinado JR, Chaplot K, Jarvela TS, Barbieri EM, Shorter J, Lindberg I. ACS Chem Neurosci. 2022 Jun 1;13(11):1651-1665. doi: 10.1021/acschemneuro.2c00156. Epub 2022 May 12.PMID: 35549000 
• Rapid and efficient testing of the toxicity of graphene-related materials in primary human lung cells. Frontiñan-Rubio J, González VJ, Vázquez E, Durán-Prado M. Sci Rep. 2022 May 10;12(1):7664. doi: 10.1038/s41598-022-11840-2.PMID: 35538131 
• Intrinsic and selective activity of functionalized carbon nanotube/nanocellulose platforms against colon cancer cells.González-Domínguez JM, Grasa L, Frontiñán-Rubio J, Abás E, Domínguez-Alfaro A, Mesonero JE, Criado A, Ansón-Casaos A. Colloids Surf B Biointerfaces. 2022 Apr;212:112363. doi: 10.1016/j.colsurfb.2022.112363. Epub 2022 Jan 25.PMID: 35123194

2021

• The Protective Effect of Ubiquinone against the Amyloid Peptide in Endothelial Cells Is Isoprenoid Chain Length-Dependent. Frontiñán-Rubio J, Rabanal-Ruiz Y, Durán-Prado M, Alcain FJ. Antioxidants (Basel). 2021 Nov 13;10(11):1806. doi: 10.3390/antiox10111806.PMID: 34829677 
• Biological Significance of the Protein Changes Occurring in the Cerebrospinal Fluid of Alzheimer’s Disease Patients: Getting Clues from Proteomic Studies. Pedrero-Prieto CM, Frontiñán-Rubio J, Alcaín FJ, Durán-Prado M, Peinado JR, Rabanal-Ruiz Y. Diagnostics (Basel). 2021 Sep 9;11(9):1655. doi: 10.3390/diagnostics11091655.PMID: 34573996 
• The Use of Coenzyme Q10 in Cardiovascular Diseases. Rabanal-Ruiz Y, Llanos-González E, Alcain FJ. Antioxidants (Basel). 2021 May 10;10(5):755. doi: 10.3390/antiox10050755.PMID: 34068578 
• mTORC1 activity is supported by spatial association with focal adhesions. Rabanal-Ruiz Y, Byron A, Wirth A, Madsen R, Sedlackova L, Hewitt G, Nelson G, Stingele J, Wills JC, Zhang T, Zeug A, Fässler R, Vanhaesebroeck B, Maddocks ODK, Ponimaskin E, Carroll B, Korolchuk VI.J Cell Biol. 2021 May 3;220(5):e202004010. doi: 10.1083/jcb.202004010.PMID: 33635313 
• Ubiquinol Supplementation Improves Gender-Dependent Cerebral Vasoreactivity and Ameliorates Chronic Inflammation and Endothelial Dysfunction in Patients with Mild Cognitive Impairment. García-Carpintero S, Domínguez-Bértalo J, Pedrero-Prieto C, Frontiñán-Rubio J, Amo-Salas M, Durán-Prado M, García-Pérez E, Vaamonde J, Alcain FJ. Antioxidants (Basel). 2021 Jan 20;10(2):143. doi: 10.3390/antiox10020143.PMID: 33498250 

2020

• Sublethal exposure of small few-layer graphene promotes metabolic alterations in human skin cells. Frontiñan-Rubio J, Gomez MV, González VJ, Durán-Prado M, Vázquez E. Sci Rep. 2020 Oct 27;10(1):18407. doi: 10.1038/s41598-020-75448-0.PMID: 33110217 
• Transcriptional block of AMPK-induced autophagy promotes glutamate excitotoxicity in nutrient-deprived SH-SY5Y neuroblastoma cells. Vucicevic L, Misirkic M, Ciric D, Martinovic T, Jovanovic M, Isakovic A, Markovic I, Saponjic J, Foretz M, Rabanal-Ruiz Y, Korolchuk VI, Trajkovic V. Cell Mol Life Sci. 2020 Sep;77(17):3383-3399. doi: 10.1007/s00018-019-03356-2. Epub 2019 Nov 12.PMID: 31720741
• A comprehensive systematic review of CSF proteins and peptides that define Alzheimer’s disease. Pedrero-Prieto CM, García-Carpintero S, Frontiñán-Rubio J, Llanos-González E, Aguilera García C, Alcaín FJ, Lindberg I, Durán-Prado M, Peinado JR, Rabanal-Ruiz Y. Clin Proteomics. 2020 Jun 5;17:21. doi: 10.1186/s12014-020-09276-9. eCollection 2020.PMID: 32518535 
• Adipose tissue depot-specific intracellular and extracellular cues contributing to insulin resistance in obese individuals. Guzmán-Ruiz R, Tercero-Alcázar C, Rabanal-Ruiz Y, Díaz-Ruiz A, El Bekay R, Rangel-Zuñiga OA, Navarro-Ruiz MC, Molero L, Membrives A, Ruiz-Rabelo JF, Pandit A, López-Miranda J, Tinahones FJ, Malagón MM. FASEB J. 2020 Jun;34(6):7520-7539. doi: 10.1096/fj.201902703R. Epub 2020 Apr 15.PMID: 32293066
• Interplay Between Mitochondrial Oxidative Disorders and Proteostasis in Alzheimer’s Disease. Llanos-González E, Henares-Chavarino ÁA, Pedrero-Prieto CM, García-Carpintero S, Frontiñán-Rubio J, Sancho-Bielsa FJ, Alcain FJ, Peinado JR, Rabanal-Ruíz Y, Durán-Prado M. Front Neurosci. 2020 Jan 29;13:1444. doi: 10.3389/fnins.2019.01444. eCollection 2019.PMID: 32063825